Are low profile tires bad for longdistance driving?

Doesn't really work that way.

Low profile tires helps in hard cornering, but can give a rougher ride and makes it easier to damage both rim and tire if you hit a pot hole. They're often fairly wide too, which usually is bad news for hydroplaning and rolling resistance.

So, if you really like your cornering and hard driving - stay with the low profiles, and drive with care in bad weather and on uneven roads.

For better durability - stay with regulars.