Yes, some people may have a natural immunity to mononucleosis, which is primarily caused by the Epstein-Barr virus (EBV). This immunity can result from previous exposure to the virus, often in childhood, leading to asymptomatic infections or mild symptoms. Genetic factors and individual immune responses also play a role in determining susceptibility to the disease. However, most people will eventually be exposed to EBV at some point in their lives.
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