What are the greatest common factors of 48 and 80?

The greatest common factors (GCF) of 48 and 80 are 1, 2, 4, and 8. To find the GCF, we identify the prime factorizations of both numbers: 48 is (2^4 \times 3) and 80 is (2^4 \times 5). The highest power of the common prime factor, which is 2, is (2^4), and the GCF is therefore 16. Thus, the GCF of 48 and 80 is 16.