How much Prednisone does the body normally produce?

The body naturally produces a steroid hormone called cortisol, which is similar to prednisone, in the adrenal glands. The average daily production of cortisol in a healthy adult is about 10 to 20 milligrams, though this can vary based on individual factors such as stress, time of day, and overall health. Prednisone is a synthetic corticosteroid that mimics cortisol's effects, and it is not produced by the body in significant amounts.