Yes, it is possible to develop a lump in the armpit (axillary lymphadenopathy) with mononucleosis, which is often caused by the Epstein-Barr virus. This condition can lead to swollen lymph nodes in various parts of the body, including the neck and armpits, due to the immune response to the infection. If you notice such a lump, it's advisable to consult a healthcare professional for proper evaluation and management.
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