What general never commanded the army of the Potomac?

General Ulysses S. Grant never commanded the Army of the Potomac, despite being a prominent Union general during the Civil War. Instead, he served as the overall commander of Union forces later in the war, while the Army of the Potomac was led by generals such as George McClellan, Ambrose Burnside, and George Meade. Grant's strategic leadership and coordination of various armies were crucial to the Union's eventual victory.