How many nautical miles from paducah KY. To Baton Rouge LA. On Mississippi river?

The distance from Paducah, KY, to Baton Rouge, LA, along the Mississippi River is approximately 350 nautical miles. This distance can vary slightly depending on the specific river route taken due to bends and meanders in the river. For precise navigation, it's advisable to consult navigational charts or a GPS system designed for marine use.