Where is dystrophin found?

Dystrophin is primarily found in muscle cells, where it plays a crucial role in maintaining the structural integrity of muscle fibers. It is located in the cytoplasm beneath the plasma membrane, specifically at the sarcolemma of skeletal and cardiac muscle cells. Dystrophin is part of a larger protein complex that connects the internal cytoskeleton of muscle cells to the extracellular matrix, helping to stabilize the muscle cell during contraction. Its absence or malfunction is associated with muscular dystrophies, particularly Duchenne muscular dystrophy.