During digestion large molecules are broken into smaller molecules by what?

During digestion, large molecules are broken down into smaller molecules primarily by enzymes. These biological catalysts facilitate chemical reactions, allowing complex carbohydrates, proteins, and fats to be hydrolyzed into simpler sugars, amino acids, and fatty acids, respectively. This process occurs throughout the digestive tract, especially in the mouth, stomach, and small intestine, enabling the body to absorb nutrients effectively.