In case of tetanus vaccine, you culture the bacteria. Then isolate the bacteria and kill the same. Then you treat the same with phenol and / or aluminium hydroxide. The killed bacteria are oxydized with potassium dichromate. So you prepare the toxoid of the same. In case of rabies vaccine, you pass the virus repeatedly through the sheep or rabbit brain to prepare the fixed strain. Then from this fixed strain the scientist has prepared the vaccine, by attenuating the strain. So the viruses are cultured, usually on cell cultures and then attenuated to prepare the vaccines. Little is known about this to medical community. All the inventions are done by the scientists. They are the 'real' heroes and doctors get the credit for everything.
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