Is it normal for my guitar calluses to itch?

Yes, it's normal for guitar calluses to itch, especially as they form and adapt to the pressure of playing. The skin may become dry or irritated, leading to an itchy sensation. To alleviate this, ensure you're keeping your hands moisturized and take breaks if the itching becomes bothersome. If the itch persists or is accompanied by pain or redness, consider consulting a healthcare professional.