Where in the treated cells is CFTR actually produced?

In treated cells, CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) is produced primarily in the endoplasmic reticulum (ER) and then transported to the plasma membrane. The CFTR protein undergoes post-translational modifications in the ER and Golgi apparatus before being folded correctly and sent to the cell surface, where it functions as a chloride channel. Proper trafficking and expression at the plasma membrane are crucial for its function in regulating ion transport.