Can you exercise and take levothyroxine?

Yes you can, I am a 39 year old white male. I currently ride bicycle's with the local club and stationary for a minimum of 1 hour per day, I have incorperated running and swimming into my current training. I only suffer one issue while running I have lower leg pain just above the ankle and below the calf, from the bottom part of the shin bone running in a band to the back of my leg, This seems to be the only issue I have with physical activity.