When did the First Philippine Constitution of 1899 or the Malolos Constitution lose its effect?

It has never "lost its effect" since it was ratified by a sovereign country known as La Republica Filipina (The Philippine Republic). The Philippine Constitution to date is considered by legal experts as a farce since it was initiated by an occupying power--the United States--through a puppet government that imposed its will and an illegal constitution on the unwilling Filipinos.