Edward VI contracted measles and smallpox when he was 14 and this left him very weak and in 1553 when he was just 15, he died of tuberculosis.
Jane Seymour, Henry's 3rd wife gave birth to his son Edward. Jane eventually died shortly after giving birth. She died of complications of childbirth. Edward VI reigned over England at the age of 8. He died when he was 15.
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