Can Zoloft 150mg be taken with Benadryl?

Zoloft (sertraline) and Benadryl (diphenhydramine) can generally be taken together, but it's essential to consult with a healthcare provider first. Combining these medications may increase the risk of side effects, such as drowsiness or dizziness, due to their sedative properties. Always follow your doctor's advice regarding medication interactions and dosages.