According to some studies, the bacterial count really doesn't change much after the first time you wear them. One student recently wore the same pair of jeans every day for a year without washing them. Bacterial cultures really did not change much throughout that year. Those studies say it really doesn't hurt to not wash them.
However, dirt will start to become visible, smells won't go anywhere, and they will start to stretch out and get saggy-butted. If you have the chance, go ahead and wash your jeans. There will be a visible difference.
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