What age does a human use the endocrine system the most?

The endocrine system is most active during puberty, which typically occurs between the ages of 10 and 14 for girls and 12 and 16 for boys. This period is characterized by significant hormonal changes that drive sexual maturation, growth spurts, and the development of secondary sexual characteristics. However, the endocrine system continues to play a crucial role throughout life, regulating various bodily functions, metabolism, and stress responses.