Who was asked to sacrifice his son in the bible?

God did not ask anyone to kill His Son, but He asked His Son to die for the sin of the world. Jesus (God's Son) said,

"The reason my Father [God] loves me is that I lay down my life-only to take it up again. No one takes it from me, but I lay it down of my own accord. I have authority to lay it down and authority to take it up again. This command I received from my Father" (John 10:17-18). So even though God used humans to kill Jesus, God Himself was the One Who sacrificed His only Son (and then rose him from the dead) because He loved the world. John 3:16 says "For God so loved the world that he gave his one and only Son, that whoever believes in him shall not perish but have eternal life."

God loves you and that He has a wonderful plan for your life.

God asked Abraham to sacrifice his son Isaac. Abraham bound Isaac and was going to kill him, but an angel intervened and Isaac was not killed. God did this so Abraham could better understand how much love God has by giving his only begotten son to be cruelly killed to save mankind.