Has God worked with people in different ways?

That kind of implies that there are people who aren't ordinary. Everyone is an ordinary person...

God can work with anyone, but his favourites are the ones who have tried to do everything in their own strength and failed. The outcasts, the underdogs. Once people have tested their own strength and found it lacking, they find it more easy to rely entirely on God, and that's when he can really do great things with them.