The waveform changes most closely associated with tissue injury are typically an increase in the amplitude and a shift in the morphology of the electrical signals observed in an electrocardiogram (ECG) or other monitoring devices. Specifically, in the case of myocardial injury, there may be ST-segment elevation or depression, T-wave inversion, and the presence of abnormal Q waves. These changes indicate impaired electrical activity due to necrosis or inflammation in the affected tissue.
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