How can you make 20 with 6 number without repeating them?

To make 20 using 6 numbers without repeating them, you can use the following equation: (5 + 4) x (3 + 2) - 1 = 20. This equation utilizes the numbers 5, 4, 3, 2, and 1 without repeating any of them to reach the target number of 20. By strategically combining these numbers using addition, multiplication, and subtraction, you can achieve the desired result.