When was Israel first inhabited?

The earliest settlements of nomadic peoples that have been discovered in Israel were found in the outskirts of Haifa and date back around 100,000 years. It is likely that there are older settlements that simply have not been discovered or did not last, but it is doubtful that they would have been significantly earlier.

Answer:

According to tradition, Adam and Chava (Eve) are buried in Hebron, Israel (Talmud, Eiruvin 53a).