Did Indians attack Jamestown colony

Yes, Native Americans, particularly the Powhatan Confederacy, attacked the Jamestown colony in Virginia. Tensions escalated between the colonists and the indigenous people due to competition for resources and differing land use practices. Notably, a significant conflict occurred in 1622 when the Powhatan launched a coordinated attack that killed many colonists, leading to a protracted period of violence and conflict between the two groups.