The Cherokee Indians feared the loss of their land and culture due to encroachment by European settlers and the U.S. government. This fear intensified with policies like the Indian Removal Act of 1830, which aimed to relocate them to territories west of the Mississippi River. Additionally, they were concerned about the erosion of their traditional way of life and the impact of disease brought by outsiders. Overall, their fears centered around survival and maintaining their identity amidst external pressures.
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