Mononucleosis, often caused by the Epstein-Barr virus (EBV), is most commonly reported in the United States, particularly among adolescents and young adults. Approximately 45% to 50% of college-aged students are estimated to contract the virus, leading to symptoms of mononucleosis. However, it is important to note that EBV is widespread globally, and most people are infected with the virus by adulthood, often without developing noticeable symptoms.
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