What is occluding junction?

Occluding junctions, also known as tight junctions, are specialized connections between adjacent cells that create a barrier to prevent the passage of substances between them. They are primarily found in epithelial tissues and play a crucial role in maintaining the integrity of cell layers by regulating paracellular transport. Tight junctions help to maintain the distinct environments on either side of the epithelium, crucial for processes like absorption and secretion. They are composed of proteins such as claudins and occludins, which interact to seal the space between cells.