Ossification means bone growth or formation. I will be disscussing breifly normal or physiological ossification because there is pathological ossification.There are two types of ossification in the human body: endochondral and intramembranous.
Most of the bones in the human skeleton , especially the long and short bones, develop via endochondrial ossification, but some including the clavicle and most of the bones of the skull( flat bones) are formed by the intramembranous type.
Intramembranous ossification , the source of most of the flat bones, is so called because it takes place within condensations of mesenchymal tissue and not by replacement of pre-existing piece of hyaline cartilage as the case in endochondral ossification. The frontal and parietal bones of the skull, as well as parts of the temporal and occipital bones and the mandible and maxilla, are formed by intra membranous ossification. This process also contributes to the growth of short bones and the thickening (not the lengthening) of long bones.
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