What was the spanish and Indian reactions in the new world?

In the New World, Spanish reactions to indigenous populations were often characterized by conquest and colonization, driven by a desire for wealth and religious conversion. The Spanish employed violence and forced labor, exemplified by the encomienda system, which exploited native peoples. In contrast, many Indigenous peoples initially reacted with curiOSity and caution, but as they experienced violence, disease, and cultural disruption, resistance and rebellion emerged, leading to significant conflict and upheaval. Overall, the interactions were marked by a clash of cultures, resulting in profound and lasting impacts on both societies.