No, a Quadro K600 and Quadro K4000 cannot work together in SLI mode, as NVIDIA's SLI technology requires identical GPUs. Additionally, the Quadro series generally does not support SLI for CAD and digital media applications, as they are optimized for different workloads. For driving a single UHD 4K display, it's best to use a single powerful GPU, such as the K4000, for optimal performance.
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