What is the cause of induration?

Induration refers to the abnormal hardening of tissue, often resulting from inflammation, infection, or the presence of a tumor. It can occur due to factors like the accumulation of inflammatory cells, fibrosis, or the deposition of collagen in response to tissue injury. Conditions such as chronic infections, autoimmune diseases, or neoplasms can also lead to induration. The specific cause typically depends on the underlying medical condition affecting the tissue.