Why pregnant women can't use skin medicines that contains retinoids?

Pregnant women are advised against using skin medications that contain retinoids due to the risk of birth defects and other developmental issues in the fetus. Retinoids, which are derivatives of vitamin A, can affect fetal development, particularly during the first trimester when the baby's organs are forming. Additionally, the potential for systemic absorption of these compounds raises concerns about their safety during pregnancy. Therefore, it is crucial for pregnant women to consult with their healthcare providers for safe alternatives.