Combining Lexapro (escitalopram), an SSRI used for depression and anxiety, with Distaril (doxepin), a sedating antihistamine often used for sleep, should only be done under a doctor's guidance. Both medications can affect serotonin levels, and their interaction may increase the risk of side effects, including sedation. It’s essential to consult a healthcare professional to evaluate the safety and appropriateness of this combination for your specific situation.
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