How long does clopidogrel stay in the system?

Clopidogrel typically has a half-life of about 6 to 8 hours, meaning it takes that long for half of the drug to be eliminated from the body. However, its effects can last longer due to its active metabolite, which inhibits platelet aggregation. Generally, clopidogrel can remain in the system for about 5 days after the last dose, depending on individual factors like metabolism and kidney function. Full recovery of platelet function usually occurs within 5 to 7 days after discontinuation.