What roles do osteoclasts and osteocytes play in endochondral ossification?

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2026-03-23 07:00

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Osteoclasts and osteocytes play crucial roles in endochondral ossification, which is the process of bone formation from cartilage. Osteoclasts are responsible for the resorption of calcified cartilage, allowing for the replacement of cartilage with bone tissue. Osteocytes, derived from osteoblasts, help maintain the bone matrix and regulate mineralization and homeostasis. Together, these cells ensure the efficient transformation of cartilage into bone, facilitating growth and the development of the skeletal system.

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