What is a function of a poly-A signal sequence?

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2026-02-22 23:50

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A poly-A signal sequence is a crucial element in the process of transcription termination and maturation of messenger RNA (mRNA) in eukaryotic cells. It signals the end of transcription and prompts the addition of a poly-A tail to the 3' end of the mRNA molecule. This poly-A tail enhances the stability of the mRNA, facilitates its export from the nucleus to the cytoplasm, and plays a role in the initiation of translation. Overall, the poly-A signal sequence is essential for proper gene expression regulation.

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