Does clarithromycin have sulfa in it?

No, clarithromycin does not contain sulfa. It is a macrolide antibiotic that works by inhibiting bacterial protein synthesis. Sulfa drugs, on the other hand, are a different class of antibiotics that contain sulfonamide. If you have a sulfa allergy, it is generally safe to use clarithromycin, but always consult with a healthcare professional before taking any medication.