Can urine or blood be used to activate Vyvanse in order to get high?

No, urine or blood cannot be used to activate Vyvanse for a high. Vyvanse (lisdexamfetamine) is a prodrug, meaning it must be metabolized in the body to become active. It is designed to be taken orally and converted into its active form through the digestive process. Attempting to use urine or blood in this manner is ineffective and dangerous.