How does eczema affect the subcutaneous layer?

Eczema primarily affects the outer skin layers, but its inflammation can extend to the subcutaneous layer over time. Chronic eczema can lead to changes in the skin barrier, resulting in increased permeability and potential damage to the deeper tissues. This can cause inflammation and discomfort in the subcutaneous layer, making it more susceptible to infections and complications. Additionally, persistent scratching can further exacerbate these effects, leading to thicker skin and altered fat distribution in the subcutaneous layer.