Depending on the hallucinogen, it may be either an agonist or an antagonist at certain receptors. Classic psychedelics such as LSD and psilocybin are 5-HT2A receptor agonists, whereas dissociatives (PCP, DXM, ketamine, etc.) are NMDA receptor antagonists. Deliriants, such as atropine and scopolamine, are muscarinic antagonists.
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