You have to take out your nose piercing for your job will it close?

It depends on how long you've had it pierced for. Even if you've had it for 2 years, taking it out for even 6 hours could make it hard to put back in. I suggest getting a retainer (http://www.bodycandy.com/cgi-bin/category/retainers) to use during work. If you just got it done within the last month or so, you need to be careful about switching it to put the retainer in. If it isn't healed, taking out the piercing can cause scarring/infection/bump. If you can, talk to the piercer about what to do.