For a 90-pound dog, the typical dosage of Benadryl (diphenhydramine) is about 1 milligram per pound of body weight, given every 8 to 12 hours. This means a 90-pound dog could receive approximately 90 milligrams of Benadryl per dose. However, it’s important to consult your veterinarian before administering any medication to ensure safety and proper dosing for your dog's specific health needs.
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