Does Sasuke care about Naruto and Sakura in Naruto Shippuden?

the massacre was orders of konoha. itachi didn't kill sasuke, not because of leaving him on a whim, not because sparing his life, and not because he thought sasuke was too weak.

Itachi couldn't kill his little brother. he didn't have the guts to kill him. itachi cared about Sasuke above all. at first itachi begged the council to at least let his primary family remain. (Mikoto, fugaku and Sasuke) they said no, so he begged to at least leave sasuke

Itachi's Goal

After the Uchiha Massacre and leaving Konoha, Itachi, instead of using the tailed beasts for his own self-interest, continued to protect the village by joining Akatsuki and keeping an eye on them, especially Sasuke, from the outside. During his time in the group, Itachi would delay his own attempts to capture the Nine-Tailed Demon Fox, indirectly leaked information about the organization to Konoha, and attempted to kill Madara through Sasuke. Before his death, Itachi gave Naruto some of his "power," telling him to continue protecting Konoha and Sasuke, should the event occur that Sasuke would plan for their village's destruction. The "power" that Itachi gave to Naruto remains unknown. so yeah he dores care for sasuke.