How old are rabbits when they start to have litters?

Rabbits can start having litters as early as 3 to 6 months of age, depending on the breed and individual development. Female rabbits, known as does, reach sexual maturity relatively quickly, and it's important for owners to consider spaying or neutering to prevent unwanted litters and health issues. Once they start breeding, does can have multiple litters each year, typically every 30 days or so.