How reset computer on Lexus 350 after battery change?

To reset the computer on a Lexus RX 350 after a battery change, first, start the vehicle and let it idle for a few minutes. Then, drive the car for about 10-15 minutes to allow the engine control unit (ECU) to recalibrate. If needed, you can also disconnect the negative terminal of the battery for 10-15 minutes and then reconnect it, which can help reset any stored settings. Finally, check that all systems are functioning properly and any warning lights have cleared.