How can beginners learn to play "Twinkle Twinkle Little Star" on the piano?

Beginners can learn to play "Twinkle Twinkle Little Star" on the piano by first familiarizing themselves with the notes and finger placements for the song. They can then practice playing the melody slowly and gradually increase the speed as they become more comfortable. Using online tutorials or beginner piano books can also be helpful in learning the song.