As pressure in the aorta rises due to atherosclerosis more ventricular pressure is required to open the aortic valve.?

As atherosclerosis progresses, plaque buildup in the aorta increases its stiffness and resistance, leading to elevated pressure levels. This heightened pressure necessitates greater force from the left ventricle to overcome the aortic pressure and open the aortic valve during systole. Consequently, the heart must work harder, which can lead to ventricular hypertrophy and increased myocardial oxygen demand over time. This can ultimately contribute to heart failure if left unaddressed.