What US city was named after a British prime minister?

The US city named after a British prime minister is Washington, D.C., which is named after George Washington, the first President of the United States. However, if you are specifically looking for a city named after a British prime minister, that would be Birmingham, named after the British city, which was associated with the industrial revolution and had notable political figures, though not directly named after a prime minister. Overall, many U.S. cities have namesakes from British origins, but the connection can vary.