Defrosting food for 48 hours is generally not safe, as it can promote the growth of harmful bacteria. Perishable items, such as meat and poultry, should be thawed in the refrigerator, cold water, or microwave rather than at room temperature. If food has been left out for more than two hours, it's best to discard it to prevent foodborne illness. Always prioritize safety by following proper defrosting methods.
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