What hormones can initiate labor?

Labor is primarily initiated by a complex interplay of hormones, with oxytocin being one of the key players, stimulating uterine contractions. Additionally, prostaglandins help to soften the cervix and promote contractions as well. Estrogen levels rise towards the end of pregnancy, which enhances the sensitivity of the uterus to oxytocin and promotes the release of prostaglandins. Cortisol and relaxin also play supportive roles in preparing the body for labor.